What is Pexeva?

Pexeva is an antidepressant prescribed medication used for four separate disorders, including major depressive disorder (MDD), generalized anxiety disorder (GAD), panic disorder (PD), and obsessive-compulsive disorder (OCD). Pexeva is in the drug group called selective serotonin reuptake inhibitors (SSRIs). SSRIs balance the activity of serotonin (a chemical in the body, responsible for modifying mood and behavior) in the brain. Taking Pexeva can help to reduce feelings of sadness, low energy, sleep difficulties, irritability, or despair. This prescription drug is non-addictive and is not a controlled substance.


Pexeva contains the following ingredients:


Be sure to read the medication guide provided by your pharmacist before beginning Pexeva. This medication should be taken orally, usually once daily in the morning. If taking Pexeva in the morning makes you sleepy during the day, speak with your healthcare provider about taking it in the evening. Taking this medication with food may help decrease nausea. Follow your healthcare providers’ instructions on how to take this medication as dosage will vary depending on your medical condition.


Pexeva is not directly available on the manufacturer’s website for purchase as this is a prescribed medication from your healthcare provider. The pricing of Pexeva will vary depending on your insurance coverage. We would recommend speaking with your insurance company for pricing information.

Possible Side Effects

Common side effects in consumers taking Pexeva include nausea, sleepiness, weakness, dizziness, feeling anxious, trouble sleeping, sexual problems, sweating, shaking, not feeling hungry, dry mouth, constipation, infection, and yawning. Serious side effects include suicidal thoughts or actions, serotonin syndrome, visual problems, severe allergic reactions, abnormal bleeding, seizures or convulsions, manic episodes, change in appetite or weight, and low sodium levels in the blood. If you are pregnant or plan to become pregnant, do not take Pexeva, as it may harm your unborn baby. Do not take Pexeva if you are allergic to the ingredients in Pexeva, take a Monoamine Oxidase Inhibitor (MAOI), take Mellaril (thioridazine), or if you take the antipsychotic medicine pimozide (Orap). There are a lot of cautions and side effects of taking Pexeva, we strongly encourage consumers to speak with their healthcare provider about this drug.

Manufacturer’s Commitment

Sebela Pharmaceuticals, the manufacturer of Pexeva, is dedicated to providing high-quality branded prescription pharmaceutical products. The manufacturer’s website does not provide any reviews or testimonials about their products, nor do they offer any satisfaction statements.

The Bottom Line

Pexeva can be used for four separate disorders, including major depressive disorder (MDD), generalized anxiety disorder (GAD), panic disorder (PD), or obsessive-compulsive disorder (OCD). This prescription drug can help to alleviate symptoms associated with these disorders and is a non-addictive medication. However, there are a lot of side effects of taking Pexeva as well as restrictions as to who is able to use this product. While most of the common side effects are manageable, there are serious risks and potential reactions that may occur. With so many side effects, we would recommend speaking with your healthcare provider about other optional medications.

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