What is Pristiq?

Pristiq is a prescription medication that is used to treat depression. Pristiq is in a class of medications called serotonin-norepinephrine reuptake inhibitors (SRNIs). Both serotonin and norepinephrine are chemicals that work to relay messages between brain cells, and Pristiq is able to affect both of these brain chemicals to alleviate depression.


Pristiq contains the following ingredients:


Be sure to read the medication guide provided by your pharmacist before beginning Pristiq. Because this a prescribed medication, the exact dosage will depend on the severity of your condition. Pristiq can be taken with or without a meal and should be taken at the same time every day. If you miss a dose of Pristiq, try to take it as soon as you remember, but do not take 2 doses of Pristiq at once. You should not stop taking Pristiq without talking to your healthcare provider. Follow your healthcare providers’ instructions on how to take this medication, as dosage will vary depending on your medical condition.


Pristiq is not directly available on the manufacturer’s website for purchase, as this is a prescribed medication from your healthcare provider. Pricing of Pristiq will vary depending on your insurance coverage. We would recommend speaking with your insurance company for pricing information. The manufacturer’s website does provide some cost-saving options for this medication (by signing up for a co-pay card).

Possible Side Effects

Common side effects of taking Pristiq include nausea, dizziness, sweating, constipation, and decreased appetite. Serious side effects include a cough that doesn’t go away, shortness of breath, chest pain, black stools, vomit that looks like coffee grounds, eye pain/swelling/redness, widened pupils, vision changes (such as seeing rainbows around lights at night), and seizures. Pristiq may also raise your blood pressure and may increase serotonin levels, very rarely causing the condition serotonin syndrome. Do not to take Pristiq if you are allergic to the ingredients, or if you have taken any medications known as MAOI in the last 14 days. If you are pregnant or plan to become pregnant do not take Pristiq as it may harm your unborn baby. There are a lot of cautions and side effects of taking Pristiq, we strongly encourage consumers to speak with their healthcare provider about this drug.

Manufacturer’s Commitment

The manufacturer of Pristiq, Pfizer, is committed to finding solutions to the most pressing health care challenges, creating better health for everyone. The manufacturer’s website does not provide any reviews or testimonials about their products, nor do they offer any satisfaction statements.

The Bottom Line

Pristiq is a prescription medication that can be used to help alleviate the symptoms associated with depression. While the cost of this prescription varies across insurances, Pristiq offers some cost-saving options on their website. However, there are a lot of side effects of taking Pristiq as well as restrictions as to who is able to use this product. While most of the common side effects are manageable, there are serious risks and potential reactions that may occur. With so many side effects, we would recommend speaking with your healthcare provider about other alternative medications.

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