This is a review for Trazodone which is manufactured by Pliva. Trazodone is an antidepressant otherwise known as a serotonin modulator.

Basic Information: What is ‘Trazodone’

Trazodone is an antidepressant that works by moderating levels of serotonin in your brain. It is still unclear how these serotonin modulators work. Trazodone has been approved by the FDA since 1981. Trazodone treats depression but may also be used to treat schizophrenia, anxiety or to put off the side effects of other medicines. It may also be used to treat insomnia.


Your doctor will prescribe you the correct dosage of Trazodone. However, depending on your prescription you may need to break these tablets in half. Extended release tablets should be taken once a day before bed and on an empty stomach.

If you miss a dose you must take it immediately, however if it is almost time for your next dose just skip the missed dose so that you do not overdose on Trazodone.

Before taking this medicine

Trazodone is an an antidepressant that is also available in a generic form. Trazodone is only available by prescription from a doctor.

Children and teenagers should not be given Trazodone.

It is unknown whether or not Trazodone will cause harm to a fetus. If you are pregnant or breastfeeding, you must consult your doctor before taking Trazodone.


The price of Trazodone will depend on your personal medical insurance policy.

What to Expect

It may take two weeks before you start to notice your symptoms beginning to wane. Your doctor will gradually increase your doses according to your responses. You must take Trazodone exactly as prescribed.

Do not stop taking Trazodone without consulting your doctor. An abrupt stop may lead to symptoms of withdrawal.

Keep an Eye Out

Antidepressants come with all kinds of potential side effects. Serious side effects may include:

  • intense depression
  • suicidal thoughts
  • rash
  • swelling in your face
  • chest pain
  • panic attack
  • fainting
  • seizure

If you experience any of these side effects you must call your doctor immediately.

More common side effects include:

  • headache
  • muscle ache
  • nausea
  • constipation
  • erectile dysfunction
  • dizziness
  • confusion
  • blurred vision

Manufacturer’s Commitment

The manufacturer does not offer a commitment or guarantee on their products. The price will depend on your personal health insurance policy. Trazodone has been approve by the FDA and has undergone clinical trials.

The Bottom Line

It is not clear to doctors how most antidepressants work except for that they moderate the level of serotonin in your brain. Taking antidepressants comes with many risks including the risk that your depression may deepen before you feel any relief. Antidepressants come with many side effects including more serious side effects like suicidal thoughts and actions. Trazodone has been approved by the FDA since 1981 under different names and has had several clinical trials however the FDA request that you report any side effects to them. Antidepressants are an effective treatment for adults suffering from serious mental conditions like bipolar disorder and OCD, however, it is not clear whether they would be an effective treatment for day-to-day anxiety and the physical manifestations of a stressful life.

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